Researchers are getting a new look at the workings of HIV and other viruses thanks to new techniques in electron microscopy. Making a vaccine against HIV has always been difficult, at least partly because the proteins on the surface of the virus change so rapidly. Better understanding the structure of the gp120/Env trimer could help in finding less-variable areas of these proteins, not usually exposed to the immune system, which might be targets for a vaccine.
Advances in electron microscopy reveal secrets of HIV and other viruses
Science Daily - 17 Nov 2014 20:24
Researchers are getting a new look at the workings of HIV and other viruses thanks to new techniques in electron microscopy. Making a vaccine against HIV has always been difficult, at least partly because the proteins on the surface of the virus change so rapidly. Better understanding the structure of the gp120/Env trimer could help in finding less-variable areas of these proteins, not usually exposed to the immune system, which might be targets for a vaccine.
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